Related Experiment Video

Updated: Jun 4, 2026

Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay
08:34

Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay

Published on: July 15, 2025

Exploring the evolutionary relationship of insulin receptor substrate family using computational biology

Chiranjib Chakraborty1, Govindasamy Agoramoorthy, Minna J Hsu

  • 1School of Bioscience and Technology, VIT University, Vellore, India.

Plos One
|March 3, 2011
PubMed

More Related Videos

Computational Reconstruction of Pancreatic Islets as a Tool for Structural and Functional Analysis07:58

Computational Reconstruction of Pancreatic Islets as a Tool for Structural and Functional Analysis

Published on: March 9, 2022

Related Concept Videos

Insulin: The Receptor and Signaling Pathways01:28

Insulin: The Receptor and Signaling Pathways

Insulin action is mediated through a receptor tyrosine kinase, akin to the IGF-1 receptor. The number of receptors per cell varies significantly, from 40 on erythrocytes to 300,000 on adipocytes and hepatocytes. The insulin receptor consists of linked α/β subunit dimers, forming a heterotetramer glycoprotein with two extracellular α subunits and two β subunits spanning the membrane. The α subunits inhibit the inherent tyrosine kinase activity of the β subunits, but this inhibition is released...