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Dose calculation in opioid rotation: electronic calculator vs. manual calculation
Herbert Plagge1, Wilhelm Ruppen, Norman Ott
1Hospital Pharmacy, University Hospital Basel, Basel, Switzerland. hplagge@uhbs.ch
A new web-based opioid conversion calculator was developed and validated. This tool significantly improves calculation accuracy and reduces time compared to manual methods, enhancing patient safety in hospitals.
Area of Science:
- Pharmacology
- Medical Informatics
Background:
- Opioid conversion requires accurate dose calculations.
- Manual methods can be time-consuming and prone to errors.
Purpose of the Study:
- To develop and validate a web-based opioid conversion calculator.
- To assess the tool's efficiency and user acceptance.
Main Methods:
- Medline search for opioid potency and dose ratio data.
- Development of a web-based calculator.
- Prospective validation and user acceptance survey.
- Cross-over trial comparing calculator to manual table.
Main Results:
- Calculator covers 24 opioid combinations across 5 administration routes.
- Correct answer rate increased from 68% (table) to 81% (calculator) (P < 0.001).
- Median calculation time reduced from 8.9 min (table) to 4.8 min (calculator).
Conclusions:
- The web-based opioid conversion calculator is validated and established.
- The tool saves time and enhances patient safety by minimizing calculation errors.
- Contributes to optimized hospital processes and patient safety.
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