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[Proteolytic and collagenolytic activities of experimental methylcholanthrene-induced fibrosarcoma]
E A Tryniszewska1, E Bańkowski
1Zakład Biochemii Akademii Medycznej, Białymstoku.
Abstract:
Rat fibrosarcoma induced by methylcholanthrene exhibited proteolytic activity against type I collagen at acidic range of pH values. This activity was not only collagen-specific as it was able to cause hemoglobin degradation to low-molecular products. No collagenolytic activity was found near physiological values pH.