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[Individualized treatment of breast cancer]

J Eucker1, K Possinger

  • 1Medizinische Klinik mit Schwerpunkt Onkologie und Hämatologie, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117 Berlin. jan.eucker@charite.de

Deutsche Medizinische Wochenschrift (1946)
|March 3, 2011
PubMed

Insights

Targeted therapy offers new breast cancer treatment options by targeting specific tumor characteristics. This review highlights key advancements, particularly for metastatic breast cancer.

Area of Science:

  • Oncology
  • Pharmacology

Context:

  • Breast cancer is the most common cancer in women, necessitating evolving treatment strategies.
  • Recent advancements include targeted therapies that exploit tumor-specific biological properties.

Purpose:

  • To review the most important targeted therapies for breast cancer.
  • To focus on the application of targeted agents in metastatic breast cancer treatment.

Summary:

  • Targeted therapies act on specific molecular targets like receptors, intracellular pathway proteins, or cytokines.
  • New treatment modalities complement traditional approaches in both adjuvant and metastatic settings.
  • Significant guideline changes have also emerged in endocrine treatment.

Impact:

  • Provides an overview of novel breast cancer treatment modalities.
  • Informs clinical practice regarding the use of targeted agents, especially for advanced disease.

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