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Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing
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Structural repertoire of immunoglobulin λ light chains

Anna Chailyan1, Paolo Marcatili, Davide Cirillo

  • 1Department of Biochemical Sciences, Sapienza University of Rome, P.le A. Moro, 5-00185 Rome (I), Italy.

Proteins
|March 3, 2011
PubMed
Summary

Immunoglobulin lambda (λ) light chains exhibit unique structural conformations and sequence constraints, differing from immunoglobulin kappa (κ) chains. This structural diversity in λ chains contributes to fine-tuning antigen recognition in the immune system.

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