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Published on: May 21, 2015
[Study of serological biochemistry index of chronic periodontitis]
Xue Zhao1, Ya-Ping Pan, Dong-Mei Zhang
1Dept. of Periodontology, School of Stomatology, China Medical University, Shenyang 110002, China.
Objective:
To investigate the effect of serum biochemistry on the development of periodontitis.
Methods:
225 participants without any system disease were involved in the study. Case group consist of 145 chronic peri-odontitis and was divided into gentle group (clinical attachment loss < 3 mm), moderate and severe group(clinical attachment loss > or = 3 mm). Control group consist of 80 periodontal healthy persons. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including glucose, lipid and calcium were analyzed. SPSS 12.0 software package was adopted to analyze the investigation results.
Results:
There's no statistically significant difference of serum, lipid and calcium between case group and control group (P > 0.05). But case group had a higher percentage of people with abnormal glucose, lipid and calcium than control group (P < 0.05). Moderate and severe group had a significantly higher serum glucose, triglyceride and lipoproteins-cholesterol than gentle group (P < 0.05).
Conclusion:
Abnormal level of serum glucose, lipid and calcium may increase the affectability of host to periodontitis and promote the inflammation in paradentium.
