[Determination of chloramphenicol residues in milk powder using molecular imprinted polymers (MIP) by LC-MS/MS]

The method is presented to analyze chloramphenicol in milk powder. Sample was clean-up by used molecular imprinted polymers (MIP). The determination was performed by LC-ESI-MS/MS. The LC was equipped with column Luna C18 Phenomenex. CAP-d5 was used as internal standards. The method was validation according to the criteria of Decision Commission No 2002/657/EC. Recoveries for the level 0.3 microg/kg was in the range 104-111%. The limit of decision (CCalpha) and detection capability (CCbeta) was respectively 0.06 microg/kg and 0.09 microg/kg.