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[Cardiovascular manifestations of seronegative inflammatory spondyloarthropathies]

Hanna Przepiera-Bedzak1, Iwona Brzosko, Małgorzata Peregud-Pogorzelska

  • 1Klinika Reumatologii i Chorób Wewnetrznych Pomorskiej Akademii Medycznej w Szczecinie ul. Unii Lubelskiej 1, 71-252 Szczecin.

Annales Academiae Medicae Stetinensis
|March 4, 2011
PubMed

Insights

Cardiovascular issues are common in seronegative spondyloarthropathies like ankylosing spondylitis and psoriatic arthritis. Early cardiac investigation is crucial for managing these patients and improving outcomes.

Area of Science:

  • Rheumatology
  • Cardiology

Context:

  • Seronegative spondyloarthropathies (SnAs) encompass a group of inflammatory diseases.
  • Cardiovascular involvement in SnAs is a significant clinical concern requiring further elucidation.

Purpose:

  • To review and highlight the cardiovascular manifestations in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA).
  • To emphasize the need for comprehensive cardiovascular assessment in SnA patients.

Summary:

  • Ankylosing spondylitis (AS) patients exhibit various echocardiographic abnormalities including ascending aortitis, valvular insufficiency, and conduction system defects.
  • Psoriatic arthritis (PsA) is associated with a higher mortality risk due to cardiovascular diseases, with reported abnormalities including pericarditis, myocarditis, and valvular disease.
  • Diastolic dysfunction in PsA correlates with disease activity and duration.

Impact:

  • Understanding these cardiac risks can lead to earlier diagnosis and intervention.
  • Improved cardiovascular monitoring in SnA patients may reduce morbidity and mortality.
  • This review underscores the importance of a multidisciplinary approach involving rheumatologists and cardiologists.

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