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Updated: Jun 4, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
A comparison of depression symptoms and histories in pregnant women
David M Haas1, Jennifer Weida, Ronda Smith
1Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, USA. dahaas@iupui.edu
Objective:
To identify the prevalence of depression symptoms in an obstetric population.
Study Design:
A cross-sectional survey of a diverse group of urban and suburban pregnant women was performed. Self-reported depression history, demographics and current depression symptoms measured by a validated survey instrument were obtained.
Results:
Of 309 women surveyed, 21.3% reported a prior or current diagnosis of depression, 47% reported past symptoms of depression and 21% noted current depression symptoms. Suburban women more often reported histories of depression, as did Caucasians, when compared with other ethnicities. A logistic regression demonstrated that prior diagnosis of depression was the strongest predictor of current depression symptoms (odds ratio 4.39, 95% confidence interval 2.12-9.07).
Conclusion:
Depression is common in pregnant women, and it is important for providers to screen patients, particularly those with a history of a depression diagnosis.
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