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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

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Related Experiment Video

Updated: Jun 4, 2026

Fabrication of Microscope Stage for Vertical Observation with Temperature Control Function
06:21

Fabrication of Microscope Stage for Vertical Observation with Temperature Control Function

Published on: July 31, 2019

Ergonomic microscope comfort and control.

Elizabeth Anne Thomas1

  • 1School of Nursing, University of California, Los Angeles, CA, USA. ethomas@sonnet.ucla.edu

AAOHN Journal : Official Journal of the American Association of Occupational Health Nurses
|March 4, 2011
PubMed
Summary

Implementing ergonomic changes in microscope use significantly reduced worker discomfort and fatigue in high-tech manufacturing. This occupational health initiative improved employee well-being and safety.

Area of Science:

  • Occupational Health
  • Ergonomics
  • Manufacturing Safety

Background:

  • Microscope use in computer chip inspection causes significant worker discomfort and injury.
  • High-technology manufacturing environments present unique ergonomic challenges for inspection personnel.

Purpose of the Study:

  • To reduce employee fatigue and discomfort associated with microscope use.
  • To implement and evaluate an ergonomics project in a microscope user environment.

Main Methods:

  • A two-phase project utilizing Total Quality Management (TQM) principles.
  • A multidisciplinary team, led by an occupational health nurse practitioner, implemented changes.
  • Interventions included equipment modification, administrative adjustments, and targeted user training.

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Last Updated: Jun 4, 2026

Fabrication of Microscope Stage for Vertical Observation with Temperature Control Function
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Published on: July 31, 2019

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin
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Mechanical Manipulation of Neurons to Control Axonal Development
10:02

Mechanical Manipulation of Neurons to Control Axonal Development

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Main Results:

  • A significant reduction in reported fatigue and discomfort among microscope users was achieved.
  • The multifaceted approach effectively addressed the ergonomic issues.
  • The project demonstrated the positive impact of targeted interventions.

Conclusions:

  • Ergonomic interventions are effective in mitigating workplace discomfort and injury.
  • Occupational health nurses are well-suited to lead health and safety improvement projects.
  • Successful implementation aligns with corporate quality initiatives and strategic objectives.