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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

Association between hypertension and coronary artery disease as assessed by coronary computed tomography

Ryoko Mitsutake1, Shin-ichiro Miura, Yuhei Shiga

  • 1Department of Cardiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, Japan.

Journal of Clinical Hypertension (Greenwich, Conn.)
|March 4, 2011
PubMed

Insights

Hypertension is strongly linked to coronary artery disease (CAD) found through coronary computed tomography (CT) scans. This study identified hypertension as a key risk factor in patients undergoing CT for suspected CAD.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Multidetector row computed tomography (MDCT) allows for noninvasive assessment of coronary artery stenosis and plaque.
  • Patient characteristics associated with coronary artery disease (CAD) detected by MDCT coronary CT are not well understood.

Purpose of the Study:

  • To investigate patient characteristics associated with CAD identified via MDCT coronary CT.
  • To determine the prevalence of hypertension, hyperlipidemia, diabetes mellitus, and metabolic factors in patients with suspected CAD.

Main Methods:

  • 513 patients with suspected CAD underwent coronary CT.
  • Quantified patient characteristics including hypertension (HTN), hyperlipidemia, diabetes mellitus (DM), visceral fat area (VFA), subcutaneous fat area, and plasma levels of adiponectin and leptin.
  • Multivariate logistic regression analysis was used to assess associations with CAD.

Main Results:

  • Hypertension (HTN) was the most significant predictor of CAD in both men and women (P=.002; P=.048, respectively).
  • In men, the percentage of CAD increased significantly with rising systolic blood pressure (trend, P=.0002).
  • No significant differences in adiponectin or leptin levels were found between patients with and without CAD, though associations with chronic kidney disease were noted.

Conclusions:

  • Hypertension is significantly associated with the presence of CAD as detected by coronary CT.
  • MDCT coronary CT is a valuable tool for assessing CAD and associated patient characteristics.

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