[A case of T-cell lymphoblastic lymphoma with multiple patchy shadows in both lung fields]

Area of Science:

• Oncology
• Hematology
• Medical Imaging

Background:

• T-cell lymphoblastic lymphoma (T-LBL) is an aggressive lymphoid neoplasm.
• Mediastinal masses can present with diverse pulmonary and pleural manifestations.
• Early diagnosis and treatment are crucial for managing T-LBL.

Observation:

• A 54-year-old male presented with nonproductive cough and back pain.
• Chest computed tomography (CT) revealed an anterior mediastinal mass, pulmonary lesions, and pleural effusion.
• Biopsies confirmed T-cell lymphoblastic lymphoma in the mediastinal mass and pleural fluid.

Findings:

• The patient was treated with the JALSG-ALL202 protocol.
• Remarkable diminution of all identified lesions was observed post-treatment.
• This case represents a rare instance of T-cell lymphoblastic lymphoma with pulmonary infiltration.

Implications:

• This case underscores the importance of comprehensive imaging and biopsy in diagnosing T-LBL.
• The successful treatment outcome suggests the efficacy of the JALSG-ALL202 protocol in managing T-LBL with extensive disease.
• Further research into rare presentations of T-LBL may improve diagnostic and therapeutic strategies.