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Updated: Jun 4, 2026

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
Published on: December 6, 2024
Intravascular photoacoustic imaging of human coronary atherosclerosis
Krista Jansen1, Antonius F W van der Steen, Heleen M M van Beusekom
1Thorax Center, Erasmus Medical Center, Rotterdam, The Netherlands. krista.jansen@erasmusmc.nl
Abstract:
We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease. A 1.25 mm diameter intravascular imaging catheter was built, comprising an angle-polished optical fiber adjacent to a 30 MHz ultrasound transducer. Specific photoacoustic imaging of lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230 nm. Simultaneous imaging with intravascular ultrasound was performed.
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