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Updated: Jun 4, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Vascular cognitive impairment: Current concepts and Indian perspective
Suvarna Alladi1, Subhash Kaul, Shailaja Mekala
1Department of Neurology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad -500082, India.
Vascular Cognitive Impairment (VCI) is a spectrum of cognitive decline caused by cerebrovascular disease. Early identification and treatment are crucial to prevent dementia progression in India.
Area of Science:
- Neurology
- Gerontology
- Public Health
Background:
- Vascular Cognitive Impairment (VCI) encompasses Vascular Dementia (VaD) and Vascular Mild Cognitive Impairment (VaMCI).
- VCI arises from the interplay of vascular risk factors (hypertension, diabetes, etc.) and cerebrovascular changes in an aging brain.
- Mixed pathologies, including Alzheimer's disease (AD) and stroke, are increasingly recognized in VCI.
Purpose of the Study:
- To highlight the growing burden of VCI in India due to cardiovascular disease, stroke, and an aging population.
- To emphasize the need for early detection and intervention to prevent progression to dementia.
- To address the challenges posed by inadequate resources and low awareness.
Main Methods:
- This study reviews the complex interplay of vascular risk factors and neuropathological changes contributing to VCI.
- It examines the increasing prevalence of mixed degenerative and vascular pathologies.
- The Indian context, with its high cardiovascular disease burden and aging demographics, is specifically considered.
Main Results:
- VCI represents a significant and growing neurological challenge in India.
- The interaction between vascular factors, stroke, and neurodegenerative diseases like AD is a key aspect of VCI.
- Early identification of cognitive impairment is essential for effective management.
Conclusions:
- VCI is a complex neurological disorder with significant implications for public health in India.
- Urgent attention is required due to inadequate resources and low awareness.
- Prompt identification and treatment of early-stage VCI are critical to mitigate progression to dementia.
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