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Updated: Jun 4, 2026

The ChIP-exo Method: Identifying Protein-DNA Interactions with Near Base Pair Precision
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Development of computational methods to search for FoxA transcription factor binding sites, their experimental

V G Levitsky1, D Yu Oshchepkov, N I Ershov

  • 1Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent'eva 10, Novosibirsk 630090, Russia.

Doklady. Biochemistry and Biophysics
|March 4, 2011
PubMed
Abstract

No abstract available in PubMed .

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Chromatin Immunoprecipitation- ChIP02:36

Chromatin Immunoprecipitation- ChIP

Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
Types of ChIP
ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...