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A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
Published on: August 4, 2021
Intrapleural fibrinolytic therapy in a neonate
1Department of Pediatrics, Military Hospital Namkum, Ranchi, Jharkhand 834010, India. amarendraprasad@rediffmail.com
Insights
Pediatric bacterial pneumonia can cause pleural effusions. Complicated parapneumonic effusions may require more than simple chest tube drainage due to loculations and viscous fluid.
Area of Science:
- Pediatrics
- Pulmonology
- Infectious Diseases
Background:
- Pleural effusions are frequent complications of pediatric bacterial pneumonia.
- Inadequate management can lead to complicated parapneumonic effusions.
Observation:
- Complicated parapneumonic effusions naturally progress to loculations and empyema.
- Simple chest tube drainage is often insufficient for these complex effusions.
Findings:
- Viscous fluid and fibrinous debris can obstruct chest tubes.
- Multiple loculations within the pleural space hinder effective drainage.
Implications:
- Advanced drainage techniques may be necessary for pediatric complicated parapneumonic effusions.
- Prompt and effective management is crucial to prevent progression to empyema.
Abstract:
Pleural effusions are common complications of pediatric bacterial pneumonias. Failure to control the pleural effusions may lead to progressive disease and can result in complicated parapneumonic effusions. The natural history of a complicated parapneumonic effusion is to develop a single loculus or multiple loculations and then progress to an empyema cavity in untreated or inadequately treated patients. Simple chest tube drainage is often inadequate in complicated parapneumonic effusions, due to the presence of viscous fluid with fibrinous debris clogging the tube ormultiple loculations in the pleural space.
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