TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy

J Liu1, D Rädler, S Illi

  • 1Department of Pulmonary & Allergy, University Children's Hospital Munich, LMU Munich, Germany.

Allergy
|March 5, 2011
PubMed
Summary

Genetic variations in Toll-like receptors (TLRs) influence T-regulatory cells (Tregs) in newborns. Maternal atopy modifies these effects, impacting immune maturation and the development of childhood atopic diseases.

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