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Evoked response audiometry in scrub typhus: prospective, randomised, case-control study.

J S Thakur1, N K Mohindroo, D R Sharma

  • 1Department of Otolaryngology-Head and Neck Surgery, Indira Gandhi Medical College, Shimla, 171001, HP, India. anujagdeep@yahoo.co.in

The Journal of Laryngology and Otology
|March 5, 2011
PubMed
Summary
This summary is machine-generated.

Scrub typhus may cause cochlear and retrocochlear damage, affecting hearing. Evoked response audiometry showed prolonged latencies, suggesting retrocochlear issues, though not fully confirmed.

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Area of Science:

  • Otorhinolaryngology
  • Infectious Diseases
  • Audiology

Background:

  • Scrub typhus is an infectious disease with potential neurological complications.
  • The impact of scrub typhus on auditory pathways remains incompletely understood.
  • Evoked response audiometry is a tool to assess auditory pathway function.

Purpose of the Study:

  • To investigate cochlear and retrocochlear damage in scrub typhus patients.
  • To utilize evoked response audiometry to assess auditory nerve and brainstem function.
  • To test the hypothesis of auditory pathway involvement in scrub typhus.

Main Methods:

  • Prospective, randomized case-control study design.
  • Inclusion of 25 scrub typhus patients and 25 age/sex-matched controls.
  • Pure tone audiometry and evoked response audiometry performed before treatment.

Main Results:

  • 23 out of 25 scrub typhus patients showed high-frequency hearing loss on pure tone audiometry.
  • Evoked response audiometry revealed prolonged absolute and interpeak latencies.
  • Two patients with normal hearing exhibited increased interpeak latencies.

Conclusions:

  • Findings suggest potential retrocochlear pathology in scrub typhus.
  • High-frequency hearing loss may influence evoked response audiometry results.
  • Further research is needed to fully confirm cochlear and retrocochlear damage.