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[Long-term neuropsychological impact of type 1 diabetes in children]

P Barat1, S Tastet, V Vautier

  • 1Service d'endocrinologie et diabétologie de l'enfant et de l'adolescent, hôpital des Enfants, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux, France. pascal.barat@chu-bordeaux.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|March 5, 2011
PubMed

Insights

Type 1 diabetes in children may affect mood and cognition. This review explores animal models, clinical studies, and imaging to understand its long-term neuropsychological impact on developing brains.

Area of Science:

  • Neuroscience
  • Endocrinology
  • Developmental Psychology

Context:

  • Increasing incidence of Type 1 diabetes in pediatric populations.
  • Potential for long-term neuropsychological sequelae in affected children.
  • Need for comprehensive understanding of diabetes impact on brain development.

Purpose:

  • To review the contribution of animal models to understanding Type 1 diabetes pathophysiology.
  • To summarize clinical findings on mood and cognitive performance in diabetic children.
  • To discuss the role of neuroimaging in assessing brain development in this cohort.

Summary:

  • Animal models provide insights into the physiopathological mechanisms of Type 1 diabetes.
  • Clinical studies indicate a higher prevalence of mood disorders and potential cognitive decrements in diabetic children.
  • Neuroimaging techniques offer valuable tools for evaluating brain development alterations.

Impact:

  • Informs clinical practice regarding monitoring and intervention for neuropsychological issues in pediatric Type 1 diabetes.
  • Highlights the importance of early detection and management of mood and cognitive changes.
  • Guides future research directions in pediatric diabetes and neurodevelopment.

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