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Lineage assays: which pathway to take?

Gay M Crooks1

  • 1University of California Los Angeles, USA.

Blood
|March 5, 2011
PubMed

The report by Ehrlich et al in this issue of Blood reveals that assigning lineage potential to hematopoietic progenitors can be a challenging task, with interpretations differing widely depending on which functional assays are used. The findings add a new angle to the controversy of how the lymphoid and myeloid lineages are related during normal differentiation of hematopoietic stem cells.

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