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Published on: December 15, 2011
Insights
Kawasaki disease, a common childhood vasculitis, can lead to acquired heart disease. Early suspicion and diagnosis are crucial for managing this condition, especially when fever is prolonged and unresponsive to antibiotics.
Area of Science:
- Pediatric Rheumatology
- Pediatric Cardiology
- Infectious Diseases
Background:
- Kawasaki disease is a leading cause of acquired heart disease in children in the US.
- It is a vasculitis that requires high clinical suspicion due to potential cardiac complications.
- Delayed diagnosis can occur as symptoms present asynchronously.
Purpose of the Study:
- To present a case of Kawasaki disease with a delayed diagnosis.
- To review the diagnostic criteria, differential diagnosis, treatment, and complications of Kawasaki disease.
Main Methods:
- Case report presentation.
- Review of diagnostic criteria for Kawasaki disease.
- Discussion of differential diagnoses and management strategies.
Main Results:
- The case highlights the challenges in diagnosing Kawasaki disease, even after multiple healthcare visits.
- Delayed diagnosis can occur despite characteristic symptoms if not recognized promptly.
- Review reinforces the importance of considering Kawasaki disease in children with prolonged fever.
Conclusions:
- Kawasaki disease necessitates a high index of suspicion in children with prolonged fever unresponsive to antibiotics.
- Prompt diagnosis and treatment are essential to prevent serious cardiac sequelae.
- Comprehensive review aids clinicians in recognizing and managing this condition effectively.
Abstract:
Kawasaki disease is one of the most common vasculidities of childhood. It is the leading cause of acquired heart disease in children in the US.1 Although its course is typically self-limited, it is important that the clinician have a high degree of suspicion for its presence in light of its potential cardiac complications. It should be included in the differential diagnosis for any child with prolonged fever that is unresponsive to antibiotics. Diagnosis is often difficult in that the symptoms tend to present at different times. Usually a detailed medical history and multiple examinations (on different days) are needed to establish the diagnosis. Here, we present the case of a boy in whom a delayed diagnosis of Kawasaki disease was made after he had made multiple visits to pediatricians and also to the Emergency Department. In addition, the diagnostic criteria, differential diagnosis, treatment, and possible complications of Kawasaki disease are reviewed here.
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