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A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Adefovir-induced Stevens-Johnson syndrome and toxic epidermal necrolysis overlap syndrome
1Nil Ratan Sircar Medical College, Department of Medicine, 138 AJC Bose Road, Kolkata 700014, West Bengal, India. drpartha73@hotmail.com
Abstract:
An increasing number of patients with chronic hepatitis B infection are being treated with the newly licensed drug, adefovir. It is an acyclic nucleoside phosphonate that is relatively safe in the dosage generally used for chronic hepatitis B. Serious adverse cutaneous drug reactions like Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) following adefovir use have not been reported. We report a case of adefovir-induced SJS and TEN overlap syndrome in a patient with chronic hepatitis B infection.
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