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Updated: Jun 3, 2026

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A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Detection and molecular cloning of the extreme 3'-end of HCV
1Virology Division, National Cancer Center Research Institute, Tokyo, Japan.
Methods in Molecular Medicine
|March 5, 2011
Abstract:
The 3'-end region of the HCV genome is composed of three characteristic elements: conventional 3'-untranslated region, subsequent poly (U) stretch, and a newly identified 3'-terminal sequence named the 3'X tail (1,2). The 3'X tail is thought to be a common structure of the HCV genome, and should have important roles in initiation and regulation of the genomic replication of HCV.

