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Sinonasal sarcoidosis. A case report.
A Mallis1, N S Mastronikolis, D Koumoundourou
1ENT Department, University Hospital of Patras, Greece. 6976154469@mycosmos.gr
European Review for Medical and Pharmacological Sciences
|March 8, 2011
Summary
Sinonasal sarcoidosis, a rare condition, can mimic chronic rhinosinusitis. Early diagnosis is crucial for effective management of this granulomatous disease affecting the nasal cavity.
Area of Science:
- Otorhinolaryngology
- Pulmonology
- Pathology
Background:
- Sarcoidosis is a multisystem granulomatous disease of unknown cause, typically affecting the lungs.
- Head and neck sarcoidosis can manifest as neck masses, parotid swelling, or facial nerve palsy.
- Sinonasal sarcoidosis is an uncommon but reported localization of the disease.
Observation:
- A 46-year-old woman presented with a six-month history of worsening nasal congestion and purulent discharge.
- Physical examination revealed nasal mucosal hypertrophy, purplish discoloration, and a granulomatous appearance of the left inferior turbinate.
- The patient had a history of pulmonary sarcoidosis.
Findings:
- Histopathologic examination of biopsy specimens confirmed sinonasal sarcoidosis.
- The clinical presentation mimicked chronic rhinosinusitis, potentially delaying diagnosis.
Implications:
- Sinonasal sarcoidosis poses diagnostic challenges due to its ability to mimic other sinonasal conditions.
- Recognition of sinonasal sarcoidosis is important for appropriate patient management and treatment.
- This case highlights the importance of considering sarcoidosis in patients with refractory chronic rhinosinusitis.
