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Maternal serum inhibin-A for predicting preeclampsia
Mohamed Nabih El-Gharib1, Ma Morad
1Department of Obstetrics & Gynecology and Clinical Pathology, Faculty of Medicine, Tanta University, Tanta, Egypt. mohgharib@hotmail.com
Objective:
To evaluate the use of late first trimester maternal serum inhibin-A concentrations in prediction of preeclampsia.
Design:
Prospective study.
Setting:
Tanta University Hospital.
Methods:
All cases (327) were subjected to complete history taking, clinical and ultrasound examination, CBC, liver function tests, estimation of 24 h urine protein and venous blood samples were taken during the late first trimester for estimation of serum level of inhibin-A.
Results:
First trimester maternal serum inhibin-A concentrations were significantly higher in women who subsequently develop preeclampsia than the corresponding values in healthy matched control pregnant women.
Conclusions:
Measurement of inhibin-A during late first trimester of pregnancy can be useful in the prediction of preeclampsia.