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Comparison of different IVIg preparations on IL-17 production by human Th17 cells

Mohan S Maddur1, Srini V Kaveri, Jagadeesh Bayry

  • 1Unité 872, Institut National de la Santé et de la Recherche Médicale Paris, F-75006, France.

Autoimmunity Reviews
|March 8, 2011
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T Cell Types and Functions01:24

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...