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Related Experiment Video

Updated: Jun 3, 2026

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg

Published on: May 31, 2019

Compartment syndrome caused by a properly functioning infusion pump.

John F Bebawy¹, Dhanesh K Gupta, Antoun Koht

¹Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. j-bebawy@northwestern.edu

Journal of Clinical Anesthesia

|March 8, 2011

Summary

This summary is machine-generated.

Compartment syndrome can occur even with properly functioning drug infusion pumps. High-pressure delivery of medications like propofol and remifentanil can lead to this serious condition.

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Area of Science:

Medical devices
Anesthesiology
Surgical complications

Background:

Compartment syndrome is a painful condition that can result from increased pressure within a muscle compartment.
Intravenous (IV) catheter infiltration is a known cause of compartment syndrome.
Limited reports exist on compartment syndrome arising from correctly functioning drug infusion pumps.

Observation:

A case study details a patient who developed compartment syndrome.
The syndrome was linked to the administration of propofol and remifentanil via a standard drug infusion pump.
The infusion pump operated correctly but delivered fluids under high pressure.

Findings:

High-pressure fluid delivery from a functional drug infusion pump can cause compartment syndrome.
This case highlights a novel mechanism for drug-induced compartment syndrome.
Propofol and remifentanil, when infused at high pressure, were implicated.

Implications:

Clinicians should consider compartment syndrome in patients receiving infusions, even with functional pumps.
This finding necessitates vigilance regarding infusion pressures and potential complications.
Further research may be needed to establish guidelines for safe infusion pump use in high-risk scenarios.