Shedding light on the mitochondrial permeability transition

Fernanda Ricchelli1, Justina Sileikytė, Paolo Bernardi

  • 1Department of Biology, University of Padova, Padova, Italy. rchielli@mail.bio.unipd.it

Summary

Researchers investigated the mitochondrial permeability transition pore, a channel in the inner mitochondrial membrane. Using photodynamic methods, they identified key roles for histidine and cysteine residues and the translocator protein in regulating this pore.

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