Related Experiment Videos
Comparison of the pharmacology of nafarelin and danazol
1Department of Obstetrics and Gynecology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115.
American Journal of Obstetrics and Gynecology
|February 1, 1990
Abstract:
The pharmacologic profiles of danazol and nafarelin differ considerably from each other. Danazol interacts with multiple classes of proteins, whereas the gonadotropin-releasing hormone agonist nafarelin interacts only with the pituitary gonadotropin-releasing hormone receptor. Differences in the molecular, endocrine, and clinical pharmacologic properties of these agents may provide clues to their varying effects in the management of women with endometriosis.