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Updated: Jun 3, 2026

Introductory Analysis and Validation of CUT&RUN Sequencing Data
Published on: December 13, 2024
Summary of confirmation cut point discussions
Holly W Smith1, Michael Moxness, Robin Marsden
1Investigative Toxicology, Eli Lilly and Company, Indianapolis, Indiana 46285, USA.
Abstract:
A subgroup of AAPS NBC Immunogenicity Workshop attendees met to discuss the current recommendations in white papers and guidance documents, to describe and discuss current practices, and to resolve concerns as to the biologically and statistically appropriate approaches to determining a confirmatory cut point for immunogenicity assays. This is a summary of our discussions and recommendations.
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