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Related Concept Videos

Overview of Fatty Acid Metabolism01:28

Overview of Fatty Acid Metabolism

Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Introduction to Membrane Traffic01:44

Introduction to Membrane Traffic

The ER, Golgi apparatus, endosomes, and lysosomes work in tandem to modify, sort, and package proteins and lipids. An integrated membrane trafficking network facilitates the back and forth shuttling of molecules within different organelles in the same cell or across the cell membrane.
The transport of soluble and membrane proteins is mediated by transport vesicles that collect cargo from one cellular compartment and deliver it to another by fusing with the target organelle membrane. The Rab...
Lipid Digestion01:06

Lipid Digestion

Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

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Updated: Jun 3, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
07:03

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

Published on: July 19, 2024

Visfatin--a review.

S S Sonoli1, S Shivprasad, C V B Prasad

  • 1Department of Biochemistry, J. N. Medical College, Nehru nagar, Belgaum - Karnataka, India. drsmitasonoli@yahoo.co.in

European Review for Medical and Pharmacological Sciences
|March 9, 2011
PubMed
Summary
This summary is machine-generated.

Visfatin, a protein from adipose tissue, regulates immune responses and glucose. Its altered levels link to diseases like obesity and diabetes, suggesting potential as a diagnostic biomarker.

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Co-staining Blood Vessels and Nerve Fibers in Adipose Tissue

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Last Updated: Jun 3, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
07:03

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease

Published on: July 19, 2024

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
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Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

Co-staining Blood Vessels and Nerve Fibers in Adipose Tissue
12:05

Co-staining Blood Vessels and Nerve Fibers in Adipose Tissue

Published on: February 13, 2019

Area of Science:

  • Endocrinology and Metabolism
  • Immunology
  • Biochemistry

Background:

  • Adipose tissue secretes visfatin, also known as Pre-B cell Colony Enhancing Factor (PBEF).
  • Visfatin functions as Nicotinamide phosphoribosyl transferase (Nampt), crucial for NAD+ salvage.
  • Its role in glucose homeostasis and insulin signaling remains debated, despite known antiapoptotic and anti-inflammatory properties.

Purpose of the Study:

  • To explore the multifaceted roles of visfatin.
  • To investigate its clinical relevance and potential as a biomarker.

Main Methods:

  • Literature review of expedited research on visfatin.
  • Analysis of studies reporting visfatin's circulatory levels in various diseases.

Main Results:

  • Visfatin exhibits immune regulatory, antiapoptotic, and anti-inflammatory actions.
  • Circulatory visfatin levels are altered in obesity, diabetes mellitus, kidney diseases, and bone disorders.

Conclusions:

  • Visfatin is a clinically relevant molecule with potential diagnostic and prognostic significance.
  • Further research is warranted to clarify its precise mechanisms in metabolic regulation.