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Updated: Jun 3, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
Published on: February 10, 2020
Toward far-field vibrational spectroscopy of single molecules at room temperature
M J Winterhalder1, A Zumbusch, M Lippitz
1Department of Chemistry, University of Konstanz, D-78457 Konstanz, Germany.
Abstract:
We propose a new scheme for the extraction of chemically sensitive vibrational information from a single fluorescent molecule at room temperature. Our approach is based on a three-photon fluorescence excitation scheme, with selectivity in the production of a vibrational population of the ground state. We estimate the expected signal in perturbation theory for a standard dye molecule, compare its magnitude qualitatively to noise and various background sources, and discuss the experimental realization of this scheme.
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