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Updated: Jun 3, 2026

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Utility of performing routine head ultrasounds in preterm infants with gestational age 30-34 weeks
Vishwanath Bhat1, Michelle Karam, Judy Saslow
1Department of Pediatrics/Neonatology, Cooper University Hospital-Robert Wood Johnson Medical School, One Cooper Plaza, Camden, NJ 08103, USA.
Insights
Routine head ultrasounds (HUS) are recommended for preterm infants under 30 weeks. This study evaluated screening HUS for infants aged 30-34 weeks, finding significant abnormalities but questioning routine screening needs.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
- Medical Imaging
Background:
- Current guidelines recommend routine head ultrasounds (HUS) for preterm infants under 30 weeks gestation.
- The incidence and clinical significance of abnormalities in slightly older preterm infants remain less defined.
Purpose of the Study:
- To determine the incidence of intraventricular hemorrhage (IVH) in preterm infants between 30-34 weeks gestational age (GA).
- To evaluate the necessity of routine screening head ultrasounds (HUS) for this specific preterm infant population.
Main Methods:
- A retrospective study included preterm infants with GA of 30-34 weeks admitted to the NICU from January 1997 to September 2007.
- Intraventricular hemorrhage (IVH) grading followed the established Papile classification system.
Main Results:
- Screening HUS were performed on 463 infants (GA 30-34 weeks).
- Overall, 5.8% of infants showed abnormal cranial ultrasound findings, including IVH or periventricular leucomalacia (PVL).
- Severe abnormalities (Grade III/IV IVH or PVL) were identified in 1.5% of infants.
Conclusions:
- A notable proportion of preterm infants born between 30-34 weeks gestation exhibit cranial ultrasound abnormalities.
- Potential selection bias may have overestimated the incidence of HUS abnormalities as not all infants received screening.
- Further research is required to assess neurodevelopmental outcomes in preterm infants with mild IVH (Grades I/II) before endorsing routine screening for this group.
Background:
The American Academy of Neurology and Child Neurology Society recommend performing routine screening head ultrasounds (HUS) on preterm infants of less than 30 weeks gestation.
Objective:
To study the incidence of intraventricular hemorrhage (IVH) and evaluate the need for screening HUS in preterm infants with gestational age (GA) of 30-34 weeks.
Design/Methods:
Preterm infants (GA; 30-34 weeks) admitted to the neonatal intensive care unit (NICU) between January 1997 and September 2007 were included in this study. Grades of IVH were defined as per the Papile classification.
Results:
Screening HUS were performed on 463 infants with GA of 30-34 weeks. Twenty-seven (5.8%) infants had abnormal cranial ultrasound (US) (IVH or periventricular leucomalacia [PVL]). The incidence of IVH ranged from 3.3% to 6.3% at various GA. Seven (1.5%) infants had severe abnormalities on HUS (grades III/IV or PVL).
Conclusions:
A significant number of infants born between 30 and 34 weeks of gestation have abnormalities on screening cranial US. Since not all infants born at 30-34 weeks of gestation received a HUS, the incidence of HUS abnormalities might have been overestimated due to a possible 'selection bias'. Additional studies are needed to examine the adverse neurodevelopmental outcomes in this group of preterm infants with mild abnormalities (IVH grades I or II) on cranial US before recommending routine screenings for IVH.
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