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[Long-term treatment with corticoids in respiratory disorders]
Revue De L'Institut D'Hygiene Des Mines
|January 1, 1977
Summary
Corticosteroids offer benefits for respiratory diseases like asthma and sarcoidosis. This review details their mechanisms, side effects, and optimal long-term use, including inhaled corticosteroids and alternate-day regimens.
Area of Science:
- Pulmonology
- Pharmacology
Background:
- Corticosteroids are crucial in managing various respiratory conditions.
- Understanding their mechanisms and side effects is essential for effective treatment.
Purpose of the Study:
- To review the mechanisms of action and side effects of corticoids in respiratory diseases.
- To present the rationale for long-term corticoid treatment in specific pulmonary conditions.
Main Methods:
- Literature review of corticoid mechanisms and clinical applications.
- Discussion of treatment strategies including alternate-day therapy and inhaled corticosteroids.
Main Results:
- Synthetic glucocorticoids with short half-lives offer advantages in pneumology.
- Alternate-day therapy and inhaled corticosteroids are effective in asthma management.
- Long-term corticoid use is beneficial for sarcoidosis and thoracic collagen diseases.
Conclusions:
- Corticoids are valuable therapeutic agents for numerous respiratory diseases.
- Optimized administration, such as alternate-day regimens, can enhance efficacy and minimize side effects.