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Related Experiment Videos

[Changes in the cranio-cervical junction in Down's syndrome].

C Amato1, M Moschini, M Cioni

  • 1Servizio di Radiologia, IRCCS Instituto per la Ricerca sul Ritardo Mentale e la Involuzione Cerebrale "Oasi" - Troina (EN).

La Radiologia Medica
|January 1, 1990
PubMed
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Instability in the cervical spine was assessed in individuals with Down syndrome. Some showed atlanto-axial and atlanto-occipital anomalies, but improved extension movements were observed.

Area of Science:

  • Orthopedics
  • Neurology
  • Genetics

Background:

  • Cervical spine instability is a concern in Down syndrome.
  • Atlanto-axial and atlanto-occipital joints are particularly vulnerable.

Purpose of the Study:

  • To evaluate cervical spine instability in Down syndrome patients.
  • To assess atlanto-odontoid space and basilar line.
  • To compare joint mobility with a control group.

Main Methods:

  • Twenty-eight subjects with Down syndrome (ages 9-29) were studied.
  • Radiographic evaluation of atlanto-odontoid space and basilar line.
  • Functional movement analysis and goniometric measurements.

Main Results:

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  • Two patients (7.2%) had atlanto-axial anomalies.
  • Three patients (10.7%) exhibited atlanto-occipital instability.
  • Down syndrome patients showed significant improvement in extension movement compared to controls.

    • Conclusions:

    • Cervical spine instability is present in a subset of Down syndrome patients.
    • Specific joint mobility, like extension, may improve in this population.
    • Further research is warranted to understand the implications of these findings.