Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oogenesis01:22

Oogenesis

Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Folliculogenesis01:20

Folliculogenesis

Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
Meiosis II02:02

Meiosis II

Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
The timing and cell division patterns of meiosis differ between males and females. In male meiosis, the centrosomes are part of the formation of the meiotic spindle. However, in oocytes, including that of humans, Drosophila,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Hybridization and Immunology in Animals: A Review.

Ecology and evolution·2026
Same author

The dynamic evolution of panarthropod germ cell specification mechanisms.

Development (Cambridge, England)·2026
Same author

Evidence for Non-optimal Codon Choice in Highly Transcribed Sex-Biased Genes of Drosophila melanogaster.

Genome biology and evolution·2026
Same author

HUH-tagged Cas9 as a platform for efficient ssODN-mediated knock-in via embryo and adult injection in insects.

Communications biology·2026
Same author

Chromosome-scale genome assembly and annotation of the two-spotted cricket Gryllus bimaculatus (Orthoptera: Gryllidae).

G3 (Bethesda, Md.)·2026
Same journal

Deletion of CEACAM1 does not affect retinal and choroidal morphology or transcriptome.

Cell and tissue research·2026
Same journal

Cardiac α2δ1 C-terminal contributes to left atrial hypertrophy in chronic ischemic heart failure, in association with changes in membrane GluN1 and p-CAMKII/p-HDAC4 signaling.

Cell and tissue research·2026
Same journal

Gill ionocytes of the Lake Magadi tilapia (Oreochromis Alcolapia grahami), an extremophilic teleost native to a highly alkaline environment.

Cell and tissue research·2026
Same journal

Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

Cell and tissue research·2026
Same journal

Effects of gestational protein restriction on autophagy dynamics during odontogenesis.

Cell and tissue research·2026
Same journal

Antennal sensilla and brain morphology during development in caddisflies.

Cell and tissue research·2026
See all related articles

Related Experiment Video

Updated: Jun 3, 2026

Accurate Follicle Enumeration in Adult Mouse Ovaries
07:27

Accurate Follicle Enumeration in Adult Mouse Ovaries

Published on: October 16, 2020

Counting in oogenesis.

Delbert A Green1, Didem P Sarikaya, Cassandra G Extavour

  • 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

Cell and Tissue Research
|March 9, 2011
PubMed
Summary
This summary is machine-generated.

Accurate cell counting is vital for animal and plant development, but the molecular basis remains unclear. This review explores cell counting mechanisms during ovarian development and oogenesis.

More Related Videos

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse
12:36

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse

Published on: September 3, 2021

Related Experiment Videos

Last Updated: Jun 3, 2026

Accurate Follicle Enumeration in Adult Mouse Ovaries
07:27

Accurate Follicle Enumeration in Adult Mouse Ovaries

Published on: October 16, 2020

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse
12:36

Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse

Published on: September 3, 2021

Area of Science:

  • Developmental biology
  • Cell biology
  • Reproductive biology

Background:

  • Precise cell and structure enumeration is essential for organismal development.
  • Molecular mechanisms governing cell number determination are largely unknown.

Purpose of the Study:

  • To review and discuss cell counting mechanisms in developmental processes.
  • To highlight known mechanisms during ovarian development and oogenesis.

Main Methods:

  • Literature review and synthesis of existing research on cell counting.
  • Focus on molecular and cellular processes in ovarian development.

Main Results:

  • Ovarian development and oogenesis provide a model system to study cell counting.
  • Several potential molecular counting mechanisms are discussed.

Conclusions:

  • Understanding cell counting mechanisms is crucial for developmental biology.
  • Further research into the molecular basis of cell number control is warranted.