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Updated: Jun 3, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

Percutaneous cannulation for extracorporeal life support.

P Ganslmeier¹, A Philipp, L Rupprecht

¹Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany. patrycja.ganslmeier@klinik.uni-regensburg.de

The Thoracic and Cardiovascular Surgeon

|March 9, 2011

Summary

Percutaneous extracorporeal life support (ECLS) is a safe procedure for critically ill patients. Careful cannulation minimizes vascular complications like bleeding and limb ischemia, ensuring patient survival.

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Last Updated: Jun 3, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

Area of Science:

Cardiovascular Medicine
Intensive Care Medicine
Vascular Surgery

Background:

Extracorporeal life-support systems (ECLS) are crucial for acute cardiopulmonary failure and interhospital transfers.
This review focuses on cannulation strategies and vascular complications at our institution.

Purpose of the Study:

To analyze the incidence of vascular complications associated with percutaneous cannulation for ECLS.
To evaluate bleeding and limb ischemia rates following femoral, subclavian, and jugular vein access.

Main Methods:

Retrospective analysis of 464 ECLS implantations via percutaneous cannulation (2004-2009).
Adverse events, focusing on bleeding and limb ischemia, were analyzed based on vessel access and ECLS type.

Main Results:

32 patients (6.9%) experienced bleeding complications, primarily after PECLA (3.9%).
15 patients (3.2%) developed limb ischemia, mostly in the veno-arterial ECMO group.
No significant difference in ischemia was noted based on demographics or cannula size; survival was unaffected.

Conclusions:

Percutaneous ECLS is a safe procedure when performed with proper vessel visualization, exposure, and cannulation.
Optimal flow and minimal complications are achievable with accurate cannula placement.
Careful technique can lead to successful ECLS outcomes.