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Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Palladium-catalyzed oxidative allylic C-H silylation

Johanna M Larsson1, Tony S N Zhao, Kálmán J Szabó

  • 1Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691, Stockholm, Sweden.

Organic Letters
|March 10, 2011
PubMed
Summary

This study introduces palladium-catalyzed allylic C-H silylation using hexamethyldisilane. The novel oxidative method achieves high regioselectivity for linear allylsilane products, advancing catalytic C-H functionalization.

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