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Persistence of yellow fever vaccine RNA in urine

Miguel J Martínez1, Anna Vilella, Tomás Pumarola

  • 1Department of Clinical Microbiology, Hospital Clínic, Barcelona, Spain.

Vaccine
|March 10, 2011
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Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...