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Updated: Jun 3, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
[Mitral valve replacement in a patient with multiple myeloma]
Ryo Noguchi1, Noritoshi Minematsu, Yoshihiro Nakayama
1Department of Cardiovascular Surgery, Osumikanoya Hospital, Kanoya, Japan.
This case study highlights successful mitral valve replacement and tricuspid annuloplasty in a patient with multiple myeloma and heart failure. Careful perioperative management is crucial for patients with multiple myeloma undergoing cardiac surgery.
Area of Science:
- Cardiology
- Hematology
- Surgical Innovation
Background:
- Multiple myeloma (MM) presents significant perioperative challenges, including bleeding tendencies and infection risk.
- Congestive heart failure secondary to mitral regurgitation requires surgical intervention.
- Concurrent management of hematologic malignancy and cardiac disease necessitates a multidisciplinary approach.
Observation:
- A 71-year-old male with untreated multiple myeloma and moderate mitral regurgitation underwent cardiac surgery.
- The patient had known complications associated with multiple myeloma, including bleeding risk.
Findings:
- Successful mitral valve replacement and tricuspid annuloplasty were performed.
- A bioprosthesis was selected due to the patient's bleeding tendency and anticipated anticoagulant therapy.
- The postoperative course was uneventful, with no major complications reported.
Implications:
- This case demonstrates the feasibility of complex cardiac surgery in multiple myeloma patients.
- Careful consideration of MM-specific complications and tailored surgical choices are vital for favorable outcomes.
- Highlights the importance of individualized perioperative strategies in managing comorbid conditions.
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