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The use of acellular dermal matrix in reconstruction of complex scalp defects

Beniamino Brunetti1, Stefania Tenna, Francesco Segreto

  • 1Plastic and Reconstructive Surgery Unit, Campus Bio-Medico University of Rome, Rome, Italy.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|March 11, 2011
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...