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Updated: Jun 3, 2026

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Published on: January 18, 2018
Manual aspiration thrombectomy in acute ST elevation myocardial infarction: New gold standard
Brent Rochon1, Youssef Chami, Rajesh Sachdeva
1Brent Rochon, Youssef Chami, Rajesh Sachdeva, Joe K Bissett, Nick Willis, Barry F Uretsky, Department of Medicine, Central Arkansas Veterans Health System, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
Insights
Thrombus aspiration (TA) during percutaneous coronary intervention (PCI) for ST-segment myocardial infarction (STEMI) is recommended, even without visible thrombus. Evidence supports TA as a valuable maneuver in STEMI PCI when thrombus is suspected.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Coronary Syndromes
Background:
- ST-segment myocardial infarction (STEMI) is a critical condition requiring prompt treatment.
- Percutaneous coronary intervention (PCI) is the primary revascularization strategy for STEMI.
- Thrombus is a universal component in the pathophysiology of STEMI.
Purpose of the Study:
- To review the evidence supporting the routine use of thrombus aspiration (TA) in PCI for STEMI.
- To discuss the limitations of current data regarding TA in STEMI.
- To provide recommendations on the use of TA during STEMI PCI.
Main Methods:
- Review of existing scientific literature and clinical evidence.
- Analysis of studies investigating the efficacy and safety of thrombus aspiration.
- Evaluation of data concerning the presence of thrombus in STEMI patients undergoing PCI.
Main Results:
- Thrombus aspiration (TA) is considered a beneficial adjunct to PCI in STEMI.
- Evidence suggests TA may improve outcomes, though limitations exist in current data.
- The presence of thrombus is nearly universal in STEMI, supporting TA's utility.
Conclusions:
- Thrombus aspiration is an important maneuver during STEMI PCI.
- Routine TA is recommended, particularly when thrombus is likely, even if not angiographically visible.
- Further research may clarify the precise role and benefits of TA in STEMI management.
Abstract:
Percutaneous coronary intervention (PCI) is the preferred method to treat ST segment myocardial infarction (STEMI). The use of thrombus aspiration (TA) may be particularly helpful as part of the PCI process, insofar as the presence of thrombus is essentially a universal component of the STEMI process. This article reviews evidence favoring the routine use of TA, and the limitations of these data. Based on current evidence, we consider TA to be an important maneuver during STEMI PCI, even in the absence of visible angiographic thrombus, and recommend it whenever the presence of thrombus is likely.
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