Cancer gene therapy with heat shock protein-65 gene
1National Heart and Lung Institute, Imperial College, London, UK.
Methods in Molecular Medicine
|March 11, 2011
Abstract:
Heat shock proteins (HSPs) are highly conserved proteins present in every living cell. Many members of the HSP family are essential for cellular functions under physiologic conditions, others are induced by various forms of cellular stress (including sudden increase in temperature) to protect cells from environmental damage (1,2). Involvement in protein folding and transport led to designation of HSPs as molecular chaperones (3).
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