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Related Experiment Video

Updated: Jun 3, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Phantom study on three-dimensional target volume delineation by PET/CT-based auto-contouring.

Tiejiao Zhang¹, Yosuke Tachiya, Yuichi Sakaguchi

¹Division of Radiological Science, Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Fukuoka Igaku Zasshi = Hukuoka Acta Medica

|March 12, 2011

Summary

This summary is machine-generated.

A threshold of 27% maximum standardized uptake value (SUV) is proposed for accurate lung tumor delineation using PET/CT. Respiratory gating in both PET and CT is recommended for precise target volume definition.

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Last Updated: Jun 3, 2026

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Novel Quantification Protocol for Cardiovascular Calcification Progression Using Longitudinal MicroPET/MicroCT Images

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Published on: November 15, 2024

Area of Science:

Nuclear Medicine
Medical Imaging
Radiotherapy Planning

Background:

Accurate delineation of target volumes in Positron Emission Tomography/Computed Tomography (PET/CT) is crucial for effective radiotherapy.
Establishing appropriate threshold values for image segmentation remains a challenge.

Purpose of the Study:

To determine optimal threshold values for delineating target volumes in PET/CT using phantom studies.
To evaluate the impact of motion and radioactivity levels on target volume delineation.

Main Methods:

Utilized a phantom with varying sphere sizes and 18F concentrations.
Acquired PET/CT data under static (sPET) and gated (gPET) modes, and helical CT (HCT) and 4-dimensional CT (4DCT).
Determined absolute SUV (T(SUV)) and percentage of maximum SUV (T%) thresholds for delineating spheres.

Main Results:

An appropriate threshold of 27% (aT%) and 2.4 (aT(SUV)) was found for all spheres.
Respiratory gating (gPET/4DCT) improved volume delineation accuracy compared to static acquisition (sPET/HCT) in motion.
Low radioactivity spheres were consistently underestimated.

Conclusions:

A threshold of 27% (T%) is proposed for auto-contouring lung tumors.
Respiratory gated data acquisition in both PET and CT is recommended for accurate target volume delineation.