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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: Jun 3, 2026

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight
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Published on: October 11, 2016

Current sunscreen controversies: a critical review.

Mark E Burnett1, Steven Q Wang

  • 1Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10022, USA.

Photodermatology, Photoimmunology & Photomedicine
|March 12, 2011
PubMed
Summary

Sunscreens effectively protect against skin cancer and do not cause vitamin D deficiency. Current evidence indicates sunscreens are safe for human health, making them a vital part of sun protection strategies.

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Area of Science:

  • Dermatology
  • Photoprotection
  • Public Health

Background:

  • Sunscreens are widely used for photoprotection against UV radiation, a carcinogen.
  • Controversies exist regarding sunscreen safety and efficacy.
  • This review addresses these controversies by examining relevant scientific literature.

Purpose of the Study:

  • To evaluate sunscreen efficacy in preventing skin cancers.
  • To assess the impact of sunscreen on vitamin D synthesis.
  • To analyze the safety and toxicity of common sunscreen ingredients.

Main Methods:

  • Reviewed studies on sunscreen use and prevention of squamous cell carcinoma, basal cell carcinoma, and melanoma.
  • Examined research on sunscreen's effect on vitamin D synthesis.
  • Analyzed toxicity data for oxybenzone, retinyl palmitate, zinc oxide (ZnO), and titanium dioxide (TiO2) nanoparticles.

Main Results:

  • Topical sunscreen use is protective against squamous cell carcinoma.
  • Sunscreen use does not lead to vitamin D deficiency in practical application.
  • No adverse health effects in humans have been demonstrated from sunscreen use.

Conclusions:

  • Sunscreens are an important component of photoprotective strategies due to established UV protection benefits.
  • Future sunscreen formulations should aim for enhanced protection.
  • Continuous monitoring of the safety of evolving sunscreen products is necessary with increased public usage.