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Published on: January 22, 2022
Fertility after colorectal resection for endometriosis: results of a prospective study comparing laparoscopy with
Emile Daraï1, Benedicte Lesieur, Gil Dubernard
1Service de Gynécologie-Obstétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie, Paris, France. emile.darai@tnn.aphp.fr
Objective:
To determine whether the surgical route of colorectal resection for endometriosis is a determinant factor for fertility.
Design:
Prospective study.
Setting:
Tertiary-care university hospital.
Patient(S):
Fifty-two patients with endometriosis were randomly assigned to laparoscopic or open surgery.
Intervention(S):
Laparoscopically assisted vs. open colorectal resection.
Main Outcome Measure(S):
Evaluation of fertility outcomes spontaneously and after assisted reproductive therapy.
Result(S):
The mean follow-up was 29 months. Among the 28 patients wishing to conceive, 11 (39.3%) became pregnant. Overall cumulative pregnancy rate at 52 months for these patients was 45.1%. For patients with or without infertility, the cumulative pregnancy rate was 37.6% and 55.6%, respectively, and the cumulative spontaneous pregnancy rate 13.3% and 36.5%, respectively. All the spontaneous pregnancies were observed in the laparoscopy group.
Conclusion(S):
This study demonstrates that spontaneous pregnancy is more frequent after laparoscopy compared with open surgery for colorectal endometriosis.
