Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Drug Dosing: Infants and Children

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...

Pharmacokinetics in Pediatric Patients: Drug Excretion

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Interobserver Variation Within Planning Target Volume and Organs at Risk in a Patient with Oropharyngeal Carcinoma: A Contouring Study with Anatomical Analysis.

Current oncology (Toronto, Ont.)·2026

Same author

Post-colonoscopy colorectal cancer incidence.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025

Same author

Feasibility of Adjuvant Radiotherapy or Chemoradiation for Elderly Patients with Squamous Cell Carcinoma of the Head and Neck, and Its Correlation with Different Comorbidity Scores: A Retrospective Cohort Study.

Cancers·2025

Same author

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg.

Acta oto-laryngologica·2024

Same author

Position statement on the definition, incidence, diagnosis and outcome of acute on chronic pancreatitis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]·2023

Same author

Pulmonary Dysfunction after Pediatric COVID-19.

Radiology·2022

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Dose reduction in pediatric computed tomography with automated exposure control.

Sedat Alibek¹, Martin Brand, Christoph Suess

¹Radiology Institute, University of Erlangen, Germany. sedat.alibek@uk-erlangen.de

Academic Radiology

|March 12, 2011

Summary

Automated exposure control (AEC) software significantly reduced radiation dose by approximately 30% in pediatric multidetector computed tomographic (CT) imaging. This dose reduction was achieved without compromising diagnostic image quality, enhancing patient safety during CT scans.

More Related Videos

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Related Experiment Videos

Last Updated: Jun 3, 2026

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Area of Science:

Radiology
Medical Imaging
Pediatric Imaging

Background:

Computed tomographic (CT) imaging use has grown substantially since the 1970s.
Multidetector CT (MDCT) offers rapid data acquisition, accelerating diagnostic procedures.
Minimizing radiation exposure is crucial for patient safety in diagnostic radiology.

Purpose of the Study:

To evaluate the effectiveness of automated exposure control (AEC) software.
To assess radiation dose reduction in pediatric patients undergoing MDCT examinations.
To determine the impact of AEC on diagnostic image quality.

Main Methods:

A total of 71 pediatric patients (age 2-13 years) were examined using MDCT.
Three regions were scanned: chest, upper abdomen, and pelvis.
Image quality was subjectively assessed, and radiation dose metrics (DLP, CTDIvol, tube current-time product) were calculated with AEC enabled.

Main Results:

A mean effective dose reduction of 30.1% was achieved (5.8 mSv vs 8.4 mSv).
Dose-length product and volume CT dose index decreased by 30.4% and 29.5%, respectively.
All images were rated as diagnostic or excellent, with no nondiagnostic images.

Conclusions:

Automated exposure control (AEC) software effectively reduces radiation dose in pediatric MDCT.
A mean dose reduction of approximately 30% is achievable with AEC.
Diagnostic image quality is maintained when using AEC software in pediatric CT examinations.