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Updated: Jun 3, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
Serous retinal detachment in hypertensive posterior reversible encephalopathy syndrome
C G Besirli1, P Sudhakar, J Wesolowski
1Department of Ophthalmology and Visual Sciences, W.K. Kellogg Eye Center, MI, USA.
Abstract:
In accelerated hypertension, vasogenic brain edema associated with PRES may represent either autoregulatory breakthrough leading to vasodilation or excessive autoregulation leading to vasoconstriction. We describe 2 patients with PRES in accelerated hypertension who had serous retinal detachments, a vasoconstrictive phenomenon. The concurrence of serous retinal detachment and PRES offers intriguing support for the idea that vasoconstriction rather than vasodilation is the mechanism of vasogenic edema in PRES.
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