Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Customizing a Cryolite Glass Prosthetic Eye

Customizing a Cryolite Glass Prosthetic Eye

Published on: October 31, 2019

Maintaining a watertight globe while operating with a temporary keratoprosthesis.

Jessica S Watson¹, Thanh-Thu T Tran, William L Porfilio

¹University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.

Retina (Philadelphia, Pa.)

|March 12, 2011

Summary

The Landers wide-field temporary keratoprosthesis (TKP) effectively creates a watertight seal in porcine eyes, maintaining 100 mmHg intraocular pressure even after vitrectomy. This reusable device offers a clear view for posterior segment surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The 3-minute Step Test predicts cardiometabolic health in children.

Cardiology in the young·2026

Same author

Kinesiophobia, Physical Activity, and Physical-Activity Self-Efficacy in Adolescents with Congenital Heart Disease.

Pediatric cardiology·2026

Same author

Physical Activity and Mental Health in Adolescents With Cardiac Arrhythmias, Cardiomyopathy, or Single Ventricle Heart Disease.

Pediatric exercise science·2025

Same author

Incidence of epiretinal membrane formation following treatment of diabetic retinopathy with panretinal photocoagulation therapy.

International journal of ophthalmology·2025

Same author

Validity and Reliability of the Tampa Scale for Kinesiophobia for Adolescents with Heart Disease.

Medicine and science in sports and exercise·2025

Same author

Peak Oxygen Consumption (V̇O 2peak ) Recovery Delay in a Pediatric Fontan Population.

Medicine and science in sports and exercise·2023

Area of Science:

Ophthalmology
Surgical Devices
Biomaterials

Background:

Temporary keratoprostheses (TKPs) are crucial for maintaining intraocular pressure during complex anterior segment surgeries.
Ensuring a watertight seal is paramount to prevent complications and facilitate procedures like pars plana vitrectomy.

Purpose of the Study:

To evaluate the watertight sealing capability of the Landers wide-field temporary keratoprosthesis (TKP).
To determine if the TKP maintains a seal at high intraocular pressures (100 mmHg) in porcine eyes.

Main Methods:

Porcine eyes underwent trephination and open-sky procedures.
A 7.2 mm trunk diameter Landers wide-field TKP was sutured to the corneas.
Watertight seal integrity was tested at 100 mmHg, both before and after pars plana vitrectomy.

More Related Videos

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Published on: June 12, 2012

Related Experiment Videos

Last Updated: Jun 3, 2026

Customizing a Cryolite Glass Prosthetic Eye

Customizing a Cryolite Glass Prosthetic Eye

Published on: October 31, 2019

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Published on: June 12, 2012

Main Results:

The Landers TKP achieved a watertight seal at 100 mmHg in all 45 tested eyes.
Following pars plana vitrectomy, 41 of 41 eyes maintained 100 mmHg without leakage.

Conclusions:

The seal is formed at the flange-cornea interface, not the stroma-trunk interface.
The Landers wide-field TKP is a reusable device providing a clear posterior view and a reliable watertight seal.
This TKP is suitable for ocular trauma cases with corneal defects up to 0.8 mm larger than the TKP trunk diameter.