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Related Experiment Video

Updated: Jun 3, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Antenatal depression: a rationale for studying exercise.

Geetha Shivakumar1, Anna R Brandon, Peter G Snell

  • 1Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA. Geetha.Shivakumar@va.gov

Depression and Anxiety
|March 12, 2011
PubMed
Summary
This summary is machine-generated.

Exercise shows antidepressant effects and may help pregnant women with depression. More research is needed to confirm exercise as a safe and effective treatment for antenatal depression.

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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Last Updated: Jun 3, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Area of Science:

  • Obstetrics and Gynecology
  • Psychiatry
  • Exercise Science

Background:

  • Major depressive disorder (MDD) during pregnancy, or antenatal depression, presents significant challenges.
  • Untreated antenatal depression has severe implications for maternal and infant well-being.
  • This review explores exercise during pregnancy and its antidepressant potential for antenatal depression.

Purpose of the Study:

  • To review current knowledge on exercise during pregnancy.
  • To examine the antidepressant effects of exercise.
  • To establish the rationale for studying exercise interventions for antenatal depression.

Main Methods:

  • A systematic literature review was conducted.
  • Searched databases included Medline, PsycINFO, CINAHL, and the Cochrane Library.
  • Included English language articles published from 1985 to January 2010.

Main Results:

  • Existing literature supports exercise's antidepressant properties.
  • Few studies specifically address exercise for antenatal depression.
  • Observational studies suggest physical activity improves self-esteem and reduces anxiety and depressive symptoms in pregnant individuals.
  • No randomized controlled trials (RCTs) have investigated exercise for treating MDD in pregnant women.

Conclusions:

  • Further systematic studies are required to evaluate exercise as a treatment for antenatal depression.
  • Research is needed to determine exercise's role in managing depression during pregnancy, considering benefits for mother and child.
  • RCTs are essential to establish the efficacy and safety of exercise interventions for pregnant women with depression.